https://vitaminsignals.com/ind....ex.php/weakness-inve
V.Lim kinase1 (LIMK1) plays an important role in dendritic spine morphogenesis and brain function. But, the mechanism of LIMK1 in epilepsy stays ambiguous. Our research indicated that LIMK1 had been upregulated within the hippocampal dentate gyrus (DG) of a pentylenetetrazol (PTZ)-kindled epilepsy rat model. Downregulation of LIMK1 reduced susceptibility to seizures when you look at the PTZ-induced rat model, whereas combined LIMK1 knockdown and jasplakinolide treatment increased the dura
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