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es of chromosome aneuploidies 1.30 times in Robertsonian translocation carriers compared with patients with RTMIDs ( = 0.026), especially for the male and young subgroups ( = 0.030, OR = 1.35 and = 0.012, OR = 1.4, while the mosaic aneuploidy abnormalities presented no statistical difference. Our study demonstrated that meiotic segregation heterogeneity of trivalent structure is associated with the carrier's gender and translocation type, and it is independent of carrier's age. ICE phenomenon exists during meiosis and then increases th
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