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Their antiproliferative activities against individual cyst cells had been investigated by MTT assay. The outcomes demonstrated that many of the synthesized compounds had antiproliferative impacts much like the research drugs gefitinib and lapatinib. In specific, (5 R )-5-(3-chloro-4-((5-(4-fluorophenyl)thiophen-2-yl)methyl)anilino)-1,2- O -isopropylidene-α-glucofuranose ( 9da ) revealed the most powerful antiproliferative impacts against SW480, A431 and A549 cell
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