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Objective To explore the correlation between the rs4705342 gene mutation in the promoter region of the miR-143/ miR-145 cluster and the risk of PCa in the Chinese Han population. METHODS We enrolled in this study 156 cases of PCa and 188 cancer-free controls. Using TaqMan SNP genotyping assay, we detected the polymorphism of rs4705342 in the promoter region of the miR-143/ miR-145 gene, and performed a stratified analysis on the family history of cancer, body mass index (BMI), age, smoking status, and alcohol consumption of the subjects. R
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