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rt opinions for reproductive medicine, toxicology, and drug safety measures. This document is accompanied by explanations from the FDA guidance(2019)and EMA guidance(202.Family members of cancer patients experience major changes in their daily lives due to their loved one's illness. The associated stress spreads across all aspects of their lives, physical, emotional, psychological and social, and due to risk of physical and mental illness posed, these family members are referred to as secondary patients. With advances in cancer medicine
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