https://www.selleckchem.com/pr....oducts/mivebresib-ab
Joints of ten bleed naive haemophilic mice served as controls. A joint bleed resulted in significant inflammation and cartilage damage in the blood-exposed joint compared with those of control animals, in both the placebo and DFX group (all p=.05). No differences in tibiofemoral or patellar inflammation (p=.305 and p=.787, respectively) nor cartilage damage (p=.265 and p=.802, respectively) were found between the blood-exposed joints of both treatment groups. On-demand treatment with DFX does not prevent joint damage fol
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