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Subsequent COS immobilization in the OPC-PDOPA level could cause promotion of cellular proliferation, polarization and cytoskeleton development. Rat bone tissue marrow mesenchymal stem cells (rBMSCs) seeded in the OPC-PDOPA-COSs revealed greater alkaline phosphatase (ALP) activity, calcium deposition, and up-regulated bone-related genetics phrase, including BMP-2, RUNx-2, COL-I and OCN. To conclude, surface biofunctionalization
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