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51, 95% CI 1.23-5.10 for PFS and HR = 2.60, 95% CI 1.19-5.67 for OS) were found to be significant predictors. Among the three indices, ALI 20.4 identified the patients with the worst 5-year outcomes. Moreover, patients with a combination of low PNI and low ALI resulted to be a better predictor of progression (HR = 5.26, 95% CI 2.01-13.73) and death (HR = 5.68, 95% CI 1.92-16.79) than low ALI and low PNI considered alone. Our results support the use of pre-treatment ALI, an easily measurable inflammatory/nutritional index, in dail
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