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Secondly, Gene Ontology (GO)-based semantic similarity information available for the genes is utilized, that helps in adding up biological relevance to the identified gene-clusters. A similarity measure is defined by integrating these two components that help in the identification of homogeneous and functionally similar groups of genes. CorGO is applied to four different types of gene expression profiles of different types of cancer. Gene-clusters identified by CorGO, are further validated by pathway enrichment, disease enrichment, and ne
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