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The prefrontal-subcortical model of emotion regulation postulates that decreased prefrontal cortex (PFC) functioning may underlie the emergence of clinical affective disorders. In addition, accumulated evidence suggests that there is considerable variability in negative affect in the nonclinical population. This study examined whether negative affective symptoms were associated with decreased PFC functioning in nonclinical young adults. Forty college students aged 18-24 years (ten males) underwent an n-back paradigm (i.e., a frontal exe
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