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A meta-analysis will be performed, if possible, and the Grading of Recommendations Assessment Development and Evaluation (GRADE). This study will use secondary data. Thus, there is no need for submission to the ethics committee. The results of this systematic review will be published in a journal after a peer-review process. Systematic review registration number CRD42020212036. Systematic review registration number CRD42020212036. The impact of manual therapy interventions on the autonomic nervous system have been largely assessed, but wit
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