https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
Resting-state striatal activity was lower 15 and 30min after nasal insulin compared to placebo. Functional connectivity of the mesocorticolimbic circuitry associated with differences in dopamine levels individuals with a stronger insulin-induced effect on dopamine levels showed a stronger increase in functional connectivity 45min after intranasal insulin. This study indicates that central insulin modulates dopaminergic tone in the striatum, which may affect regional brain activity and connectivity. Our results deepen the
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