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To clarify the need for post-operative radiation treatment in skull base chondrosarcomas (SBCs). A retrospective analysis of patients with grade I or II SBC. Patients were divided according to post-surgical treatment strategies (A) planned upfront radiotherapy and ( watchful waiting. Tumor control and survival were compared between the treatment groups. The median follow-up after resection was 105months (range, 9-376). Thirty-two patients (Grade 1, n = 16; Grade 2, n = 16) were included. The most frequent location was petroclival (21,
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