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50 and 0.43, respectively, p 0.001). Extrinsic AD patients were more likely to have higher mean SCORAD (p 0.001), CCL17 (p 0.001), CCL26/eotaxin-3 (p 0.001), and eosinophil count (p 0.001) than intrinsic AD patients. Predictive models for SCORAD identified CCL17, CCL27, serum total IgE, IL-33, and IL-5 as the most important predictors for SCORAD, but with weaker associations than single cytokines. Specific immunoinflammatory biomarkers in the serum, mainly of the Th2 pathway, are correlated with disease severity in
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