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Studies rarely examined (a) OUD treatment in general health care or prescription OUD (each 6 % of all studies and RCTs), (b) effects of social assistance (employment, education, social support) and harm reduction (each 6 % of studies; 7 % of RCTs), and (c) health-related quality of life and satisfaction with care (each 10 % and 15 % of all studies and RCTs, respectively). Scant evidence is available on the putative rehabilitative effects of psychosocial interventions, either as stand-alone treatments or in an a
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