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More, these variants had been reviewed making use of MutPred which identified 9 variations become very pathogenic. ExAC database disclosed that every the pathogenic mutations had a minor allele regularity significantly less than 0.01. The in silico analysis revealed very pathogenic mutations in amelogenin gene that could have a putative organization with amelogenesis imperfecta. These mutations is screened in patients for early analysis of susceptibility to AI.Paulownia tomentos
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