https://www.selleckchem.com/pr....oducts/asciminib-abl
© 2020 Wiley-VCH Verlag GmbH Co. KGaA, Weinheim.Enzyme promiscuity has important implications in the field of biocatalysis. In some cases, structural analogues of simple metabolic building blocks can be processed through entire pathways and, thereby, lead to natural product derivatives, which are not readily accessible by chemical means. In this study, we explored the plasticity of the aurachin biosynthesis pathway regarding the utilization of fluoro- and chloroanthranilic acids, which are not abundant in the bacterial pr
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