https://www.selleckchem.com/
Antimicrobial resistance is a major global threat to human health due to the rise, spread and persistence of multidrug-resistant bacteria or 'superbugs'. There is an urgent need to develop novel chemotherapeutics to overcome this overarching challenge. We have derivatised a clinically used fluoroquinolone antibiotic ciprofloxacin and complexed it to a copper phenanthrene framework. This has resulted in the development of two novel metallo-antibiotics of general formula [Cu(N,N)(CipHA)]NO3 where N,N represents a phenanthrene ligand and CipHA stands for a hyd
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