https://www.selleckchem.com/products/kya1797k.html
PURPOSE OF REVIEW Describe the controversial aspects of hyperprogressive disease (HPD) definition, mechanisms, and biomarkers. RECENT FINDINGS Although immune checkpoint inhibitors (ICIs) demonstrated a survival benefit in non-small cell lung cancer (NSCLC), an acceleration of tumor growth during ICI, defined as HPD, was reported in ~ 13-26% of NSCLC patients and correlated with worse survival compared with conventional progression. Different criteria have been used for HPD definition. The main limitation for the use of tumor growth ra
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