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During the past 10 years, novel treatments are developed including antiangiogenic medications focusing on vascular endothelial growth factor and its receptors, protected checkpoint inhibitors, and mammalian target of rapamycin inhibitors that have led to a substantial improvement in medical outcomes in a traditionally difficult-to-treat disease. These brand-new medications, nevertheless, likewise have essential unwanted effects and toxicities that often have an impact regarding the remedy for these patients. Making use of anti-angio
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