https://www.selleckchem.com/pr....oducts/Cyclopamine.h
Simultaneous voltage recording and intracellular Ca2+ imaging showed that modification of phase 1 to a non-failing human phenotype improved the rate of rise and magnitude of the Ca2+ transient. Ito,f expression also reduced AP triangulation but did not affect ICa,L and INa magnitudes. This raises the possibility for a new gene-based therapeutic approach to HF based on selective phase 1 modification. Patients with chronic non-specific low back pain (CNSLBP) were found with impaired postural control in previous studies. Since the trun