https://www.selleckchem.com/products/gant61.html
Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental disorders with considerably increased risk in male infants born preterm and with neonatal infection. Here, we investigated the role of postnatal immune activation on hippocampal synaptopathology by targeting Reelin+ cells in mice with ASD-like behaviours. C57/Bl6 mouse pups of both sexes received lipopolysaccharide (LPS, 1mg·kg ) on postnatal day (P) 5. At P45, animal behaviour was examined by marble burying and sociability test, followed by ex vivo brain MRI diffusion
Aimer
Commentaire
Partagez
