https://www.selleckchem.com/pr....oducts/crt-0105446.h
Inconsistent results across regions have been reported in a number of recent large trials. In this research, by reviewing results from studies that showed inconsistent treatment effects, and summarizing lessons learned, we provide some recommendations for minimizing the chance of inconsistency and allowing more accurate interpretation when such signs of heterogeneity arise, for example keep the number of regions for consistency evaluation at a minimum to avoid observing false inconsistency signals; proactively address in the protoco
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