https://www.selleckchem.com/pr....oducts/Triciribine.h
Dysregulation or mutation of DNA binding proteins such as transcription factors (TFs) are associated with the onset and progression of various types of disease, including cancer. Alteration of TF activity occurs in numerous cancer tissues due to gene amplification, deletion, and point mutations, and epigenetic modification. While cancer-associated TFs are promising targets for cancer therapy, development of drugs targeting these TFs has historically been difficult due to the lack of high-throughput screening methods. Recent advances
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