https://www.selleckchem.com/sc....reening/inhibitor-li
Moreover, Ephrin B2 was increased after HG incubation. Ephrin B2 siRNA attenuated HG-induced expression of EndMT-related markers. Furthermore, HG increased the expression of FAK and phosphorylated FAK (pho-FAK) in HAECs. In contrast, blocking Ephrin B2 could partially attenuate HG-induced FAK activation. And FAK siRNA further inhibited the EndMT-related markers in HAECs treated with HG. HG-induced EndMT in HAECs might be partially mediated by Ephrin B2 and the downstream FAK pathway. HG-induced EndMT in HAECs might be partial
Respect!
Kommentar
Delen
