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model group (p0.05). TUNEL-positive cells increased significantly in both model group and miR-182 mimics group when compared with normal group (p0.05). However, they were remarkably reduced in miR-182 mimics group when compared with model group (p0.05). Compared with normal group, model and miR-182 groups exhibited substantially decreased SOD content and increased MDA content (p0.05). MiR-182 inhibits oxidative stress and epithelial cell apoptosis in the lens of cataract rats by activating the PI3K/Akt signaling pathway.
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