https://transferase-signal.com..../index.php/a-case-st
The purpose of this study was to investigate Ca2+ signaling and also the effectation of Ca2+ in the Staphylococcus aureus multidrug resistant efflux pump LmrS. We hypothesized that antibiotics act by increasing Ca2+ concentrations, which in turn boost the efflux activity of LmrS. These Ca2+ transients were calculated by luminometry in response to various antibiotics utilizing the photoprotein aequorin reconstituted within live microbial cells. Efflux related to LmrS was calculate
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