https://www.selleckchem.com/pr....oducts/crenolanib-cp
Congenital long QT syndrome type 2 (LQT2) results from KCNH2 mutations that cause loss of Kv11.1 channel function which can lead to arrhythmias, syncope, and sudden death. Here, we generated three human-induced pluripotent stem cell (iPSC) lines from peripheral blood mononuclear cells (PBMCs) of two LQT2 patients carrying pathogenic variants (c.1714G A and c.2960del) and one LQT2 patient carrying a variant of uncertain significance (c.1870A T) in KCNH2. All lines show typical iPSC morphology, high expression of pl
Gefällt mir
Kommentar
Teilen
