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Significantly, the stress-responsive genes were downregulated, and fertility-related genes were upregulated in treatment groups. A significant correlation had been noticed among the genes studied HIF1A with MTA1 (P less then 0.05) and MTF1 with EGFR, TIMP2, TNFa, and NOS3 (P less then 0.01) respectively. The organic Zn and Cu feeding modulated the expression of stress- and fertility-related genes and protein abundance, thereby improved the sperm characteristics.Liver ischemia and reperfusion could cause serious damage to liver tissue
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