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1% (p value 0.002) lower male proportion compared to other studies. Studies conducted to date suggest ATTRwt disproportionally affects males. The proportion of males was significantly impacted by the age at diagnosis and method diagnosis, which may suggest important gender-based differences in the clinical manifestation and diagnostic challenges of ATTRwt in females that warrant future research. Studies conducted to date suggest ATTRwt disproportionally affects males. The proportion of males was significantly impacted by the age at dia
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