https://sykreceptor.com/index.....php/affirmation-asso
Aire is a transcriptional controller in medullary thymic epithelial cells (mTECs) modulating a set of peripheral muscle antigens (PTAs) and non-PTA mRNAs as well as miRNAs. Even miRNAs exerting posttranscriptional control of mRNAs in mTECs, the structure of miRNA-mRNA networks may vary. Under lowering of Aire expression, sites exhibited higher miRNA diversity controlling mRNAs. Variants in the amount of 3'UTR binding sites of Aire-dependent mRNAs may portray a crucial factor that influence the miRNA c
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