https://www.selleckchem.com/pr....oducts/INCB18424.htm
young monkeys, greater in the abdominal vs. the thoracic aorta and greatest in the iliac artery. In addition, more immature and less cross-linked fibers of collagen were found in the aortas of young females. Conclusions Aortic stiffness increased in old pre-menopausal female monkeys, more so in the abdominal aorta than in the thoracic aorta. Histological mechanisms mediating the increased aortic stiffness were augmented in the old pre-menopausal females, greater in the abdominal vs the thoracic aorta, and greatest in the iliac artery.
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