https://www.selleckchem.com/pr....oducts/smoothened-ag
1061G T) variant had impaired insulin promoter regulation activity. Moreover, this variant was found to impair insulin expression and insulin secretion in pancreatic beta cells. The proband had better blood glucose control without staple food intake ( 0.05). Herein, for the first time, we report a novel (c.1061G T) monogenic mutation associated with MODY7. This variant has impaired insulin promoter regulation activity and impairs insulin expression and secretion in pancreatic beta cells. Therefore, admi
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