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MR-Egger intercept test was conducted to detect the potential directional pleiotropy. In total, nine SNPs were identified as valid instrumental variables in our two-sample MR analysis. Fixed-effect IVW analysis indicated no evidence of causal association of genetically predicted Hcy with AF. The odds ratio (OR) and 95% confidence interval (CI) of AF per standard deviation (SD) increase in Hcy were 1.077 (0.993, 1.168), = 0.075. Similar results were observed in the sensitivity analyses. MR-Egger intercept test suggested no evidence of po
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