https://www.selleckchem.com/products/PD-98059.html
Autophagy is crucial for neuronal integrity. Loss of key autophagic components leads to progressive neurodegeneration and structural defects in neuronal synapses. However, the molecular mechanisms regulating autophagy in the brain remain elusive. Similarly, while it is widely accepted that protein turnover is required for synaptic plasticity, the contribution of autophagy to the degradation of synaptic proteins is unknown. We find that BDNF signaling via the tropomyosin receptor kinase B (Trk and the phosphatidylinositol 3-kinase (PI
إعجاب
علق
شارك
