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Atropine eye drops are a common and effective treatment for slowing myopia progression, but the site and mode of action of atropine in controlling myopia are unclear. We investigated the early retinal sites of action of atropine by examining its effects on the human full-field electroretinogram (ffERG). Baseline ffERGs were recorded in both eyes of 24 healthy subjects (mean ± SD 21.0 ± 2.3years; spherical equivalent refraction, range + 1.63 to - 0.75 D) using 6 standard ISCEV protocols, 30min after bilateral pupil dilation with 1% Tropicam
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