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The consequences of 3D culture size and morphology on the uptake and distribution of sensitizer and gene expression had been examined. Photocytotoxity, mode of cell demise, and protein expression had been compared for 2D and 3D designs. Regular and irregular NPC spheroids had been gotten from MCL and MCS practices, respectively. A significantly down-regulation of LMP1 mRNA were observed in MCL spheroid. The sensitizer uptake in 3D sp
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