https://www.selleckchem.com/pr....oducts/kartogenin.ht
The first metal-free ring opening/trifluoromethylthiolation of cycloalkanols for the formation of remote C(sp3)-SCF3 bonds has been developed. A variety of trifluoromethylthiolated carbonyl compounds that are otherwise difficult to achieve were prepared in good yields under mild reaction conditions. The reaction is assumed to proceed via C-C bond cleavage of the alkoxyl radical species generated via a photoredox-enabled intramolecular proton-coupled electron transfer process, followed by trifluoromethylthiolation of the resulting C-c
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