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Presently marketed OTC products indicated for such used in america include relevant solutions of tetrahydrozoline 0.05%, naphazoline 0.012% to 0.03per cent, and brimonidine 0.025%. All 3 agents are adrenergic receptor agonists but differ within their receptor-binding profiles tetrahydrozoline is a selective α1 receptor agonist; naphazoline is a mixed α1/α2 receptor agonist; and brimonidine is a selective α2 receptor agonist. These OTC decongestants produce vasoconstriction of conjunctival blood vessels, whic
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