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With great interest, I have read the systematic review in your journal [...]. To assess the prognosis of AF patients with or without cardiac or extra-cardiac concomitant conditions. All consecutive patients diagnosed with AF admitted to French hospitals between 2011 and 2020 were identified. Patients were classified into four groups (1) 60 yo; (2) with known cardiac disease (KCD group); (3) with extra-cardiac comorbidities (ECC); and 4) AF without KCD or ECC ("Lone AF". Altogether 2,435,541 patients were identified, from which 2,20
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