https://www.selleckchem.com/products/eht-1864.html
Age-associated decline of the immune system is referred to as immunosenescence. The E3 ligase RING finger 10 (RNF1 has long been associated with the innate immune response, although a potential role in immunosenescence has not previously been reported. In the present study, we identified that RNF10 expression is lower in aged mouse macrophages than in young cells. After lipopolysaccharide stimulation, RNF10 expression remained at a basal low level in aged mouse cells, but declined sharply in young mouse cells. Knockdown of RNF10 enha
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