https://www.selleckchem.com/
Clostridioides difficile infections (CDI) has emerged worldwide as a serious antimicrobial-resistant healthcare-associated disease resulting in diarrhea and pseudomembranous colitis. The two cytotoxic proteins, toxin A (TcdA) and toxin B (Tcd are the major virulence factor responsible for the disease symptoms. We examined time-dependent oxidative detoxification of TcdA and TcdB using different molar ratios of proteinCu2+H2O2. The metal-catalyzed oxidation (MCO) reaction in molar ratios of 1601000 for proteinCu2+H2O2 at pH 4.5 resulted in a significant 6 l
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