https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
The bla -bearing plasmid, pKPCZA02_4, was 93.3 Kb, IncI1-I type, and conjugative; bla was located in an IS1294-mediated transposon. Plasmid conjugation and DNA fragment cloning proved that bla was responsible for CAZ/AVI resistance. Our study identified conjugative plasmid-mediated bla as a new mechanism for CAZ/AVI resistance in clinical KPC-Kp strains. Careful monitoring of CAZ/AVI susceptibility is imperative for preventing the spread of the resistance gene. Our study identified conjugative plasmid-mediated blaCMY-172 a
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