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Increased activity of the initial I regimen reduced total medical expenditure significantly for unilateral, and mildly for bilateral total thyroidectomy both with initial 30-99mCi I. For patients with specific thyroidectomy for differentiated thyroid cancer, a high initial regimen of I treatment is more effective than the low activity regimen. An increased activity of the initial I regimen significantly reduced the total treatment number and medical expenditure. For patients with specific thyroidectomy for differentiated thyroid cancer,
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