https://www.selleckchem.com/
p.) from the 6 day, to 10 day significantly inhibited cold and mechanical allodynia expression. To address the concerns associated with the effectiveness of chemotherapy agents on the tumor, we evaluated paclitaxel cytotoxicity effect in combination with doxepin. Our observations indicate that doxepin even at high concentrations (1 and 10 μg/ml) does not interfere with the cytotoxic effect of paclitaxel (0.05 μg/ml). These results indicate that doxepin, when administered during chemotherapy, can prevent the development and expression of paclitaxel-induced n
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