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Notably, at clonal thickness, the colony-forming ability of MSCs ended up being significantly lower in the clear presence of 10 µM Ag+, recommending that a subpopulation of clonal MSCs ended up being delicate to Ag+ exposure. At a molecular level, surviving colony-forming MSCs treated with Ag+ demonstrated a substantial upregulation of aspects of the peroxiredoxin/thioredoxin path and operations involved with glutathione metabolism compared to untreated setting
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