https://www.selleckchem.com/pr....oducts/bay1251152.ht
e considered, but individual effects should be carefully evaluated and treatment discontinued if no effects are found. A subset of patients with chronic constipation has associated slow colonic transit and reduced faecal bile acid excretion. In addition to traditional approaches to treat chronic constipation, a novel therapeutic option is to increase the colonic concentration of intraluminal bile acids. This can be achieved through inhibition of the ileal bile acid transporter. To evaluate the evidence for efficacy and safety of an i
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