https://www.selleckchem.com/pr....oducts/trimethoprim.
Amiodarone (AM) is a highly efficient drug for arrhythmias treatment, but its extra-cardiac adverse effects offset its therapeutic efficacy. Nanoparticles (NPs)-based delivery system could provide a strategy to allow sustained delivery of AM to the myocardium and reduction of adverse effects. The primary purpose was to develop AM-loaded NPs and explore their ameliorative effects versus off-target toxicities. Polymeric NPs were prepared using poly lactic-co-glycolic acid and their physicochemical properties were characterized. Anima
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