https://www.selleckchem.com/pr....oducts/PD-0332991.ht
Increasing frataxin protein levels through gene therapy is envisaged to improve therapeutic outcomes for patients with Friedreich's ataxia (FRDA). A non-viral strategy that uses submicrometer-sized multilayered particles to deliver frataxin-encoding plasmid DNA affords up to 27 000-fold increase in frataxin gene expression within 2 days in vitro in a stem cell-derived neuronal model of FRDA.Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) imaging has been extensively used to determine the distributions of metal
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