https://arq092inhibitor.com/th....e-effects-associated
Right here, we report on an affinity-based enrichment method that permits the targeted recognition of potential substrate proteins associated with the different E6-E6AP complexes by a combination of E3-selective ubiquitination in whole-cell extracts and high-resolution MS. The basis when it comes to selectivity for this method could be the utilization of a ubiquitin variant that is effectively employed by the E6-E6AP complexes for ubiquitination although not by E6AP alone. By this proce